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自身免疫性甲状腺疾病(AITD)是育龄妇女常见的甲状腺疾病,是导致妊娠丢失的一个危险因素,它以细胞凋亡所致甲状腺滤泡破坏和激素合成受损为特点,不孕症患者中AITD的发生比例更高。日益增多的研究证据表明,AITD影响体外受精-胚胎移植(IVF-ET)的治疗效果,从促排卵过程、获卵数、卵子质量、授精过程以及胚胎质量、着床率、流产率各个环节均可能影响IVF-ET的治疗结局。对AITD患者进行IVF-ET时的提前干预近年来引起各国学者关注,但对其具体干预措施及监测管理尚需要进一步的研究。
Autoimmune thyroid disease (AITD) is a common thyroid disease in women of childbearing age is a risk factor for pregnancy loss, which is characterized by apoptosis of thyroid follicular damage and impaired hormone synthesis in infertility patients with AITD The occurrence of a higher proportion. A growing body of evidence suggests that AITD affects IVF-ET outcomes in terms of ovulation, number of oocytes retrieved, egg quality, fertilization, embryo quality, implantation rate, and miscarriage rate May affect the treatment outcome of IVF-ET. In recent years, the early intervention of IVF-ET in AITD patients has drawn the attention of scholars from all countries, but further research is needed for its specific interventions and monitoring management.