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目的探讨他汀类药物对出血性脑卒中患者神经功能及日常生活能力恢复的作用。方法选择住院的出血性脑卒中患者254例,其中给予他汀类药物治疗45例患者为观察组,给予常规治疗的209例患者为对照组,治疗前后比较2组患者神经功能缺损的程度和日常生活能力。结果治疗前2组患者ESS评分比较差异无统计学意义(P>0.05),治疗7d后2组患者ESS评分均显著下降,且观察组ESS评分低于对照组,差异均有统计学意义(P<0.05);治疗21d和30d后2组患者Barthel指数均显著升高,且观察组Barthel指数高于对照组,差异均有统计学意义(P<0.05)。结论他汀类药物能够改善出血性脑卒中患者的预后状况,促进神经功能的恢复,降低致残率,提高患者的生活质量,值得临床推广应用。
Objective To investigate the effect of statins on the recovery of neurological function and daily living ability in patients with hemorrhagic stroke. Methods A total of 254 patients with hemorrhagic stroke were enrolled in this study. Among them, 45 patients were treated with statins and the other 209 patients treated with statins were compared. The degree of neurological deficits and daily life were compared between the two groups before and after treatment ability. Results There was no significant difference in ESS score between the two groups before treatment (P> 0.05). After 7 days of treatment, the ESS scores of two groups were significantly decreased, and the ESS scores of the observation group were lower than those of the control group (P <0.05). The Barthel index of two groups was significantly increased after 21d and 30d, and the Barthel index of the observation group was higher than that of the control group (P <0.05). Conclusion Statins can improve the prognosis of hemorrhagic stroke patients, promote the recovery of neurological function, reduce the morbidity and improve the quality of life of patients, which is worthy of clinical application.