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[目的]研究大气污染物与中风总死亡及两种不同类型中风死亡间的关联,确定大气污染环境中风死亡易感人群。[方法]收集上海市2003—2008年大气污染及中风死亡数据,采用时间分层-病例交叉设计方法分析两者间相关关系。[结果]所研究大气污染物与不同类型中风死亡均存在相关关系,当暴露于大气中的二氧化硫(SO2)与二氧化氮(NO2)时,心脏病患者的缺血性中风死亡风险提高。当SO2与NO2两种污染物每增加10μg/m3时,导致心脏病患者死于缺血性中风的比值比(95%可信区间)分别为1.057(1.010~1.107)与1.076(1.023~1.131),高于在同等条件下非心脏病患者所面临的缺血性中风死亡风险。本研究并未发现高血压与糖尿病存在类似的修饰效应。[结论]大气污染物能够增加人群中风死亡风险,心脏病患者更易诱发中风。
[Objective] To study the relationship between air pollutants and total death of stroke and the death of two different types of stroke, and to determine the susceptible population of stroke death due to air pollution. [Method] The data of air pollution and stroke death in Shanghai during 2003-2008 were collected. The relationship between them was analyzed by time stratification-case cross design method. [Results] There was a correlation between the air pollutants studied and the deaths of different types of stroke. When exposed to SO2 and NO2 in the atmosphere, the risk of ischemic stroke increased in patients with heart disease. The odds ratio (95% confidence interval) of patients with heart disease who died of ischemic stroke was 1.057 (1.010-1.107) and 1.076 (1.023-1.1331) respectively for each 10 μg / m3 increase of SO2 and NO2. , Which is higher than the risk of ischemic stroke facing non-heart disease patients under the same conditions. This study did not find a similar modified effect of hypertension and diabetes. [Conclusion] Air pollutants can increase the risk of death from stroke in stroke patients, and stroke patients are more likely to be induced by heart disease.