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脊柱骨巨细胞瘤是一种原发于脊柱的良性肿瘤,血运丰富,侵袭性生长,易复发,并可发生肺转移,因此治疗难度大。文中综述了各种治疗方法及其效果,包括外科治疗、放射治疗、动脉栓塞治疗及其发生肺转移时的治疗方法。结果显示:目前,对于脊柱骨巨细胞瘤,最有效的治疗方法是广泛或边界的整块切除,如果不能达到边界切除,则应辅助放射治疗,消灭可能残留的肿瘤细胞,巨大的骶骨骨巨细胞瘤可采用连续动脉内栓塞治疗。对于发生肺转移的脊柱骨巨细胞瘤,可以通过肺叶切除和(或)采用化疗来控制。
Giant cell tumor of the spine is a benign tumor originating in the spine. It is difficult to treat due to its rich blood supply, aggressive growth, easy recurrence and lung metastasis. The article reviewed various treatments and their effects, including surgical treatment, radiotherapy, arterial embolization and treatment of lung metastases. The results show that at present, the most effective treatment for giant cell tumor of the spine is extensive or borderline resection, and if borderline resection can not be achieved, radiation therapy should be assisted to eliminate possible residual tumor cells, giant sacral giant bone Cell tumors can be treated with continuous arterial embolization. Spinal giant cell tumor of the lung metastases can be controlled by lobectomy and / or chemotherapy.