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目的观察多瑞吉联合伽玛刀治疗晚期难治性癌性疼痛的临床疗效和不良反应。方法对50例难治性癌痛的晚期体部肿瘤患者给予多瑞吉及非甾体类药物,同时应用螺旋CT薄层扫描、定位,根据肿瘤性质、类型、部位等制订治疗计划后,进行体部伽玛刀治疗。主诉疼痛分级(VAS法)进行疼痛评定。结果疼痛有效缓解率[完全缓解(CR)+部分缓解(PR)]为96%。结论对晚期难治性癌性疼痛且吗啡类镇痛药不能耐受或出现不良反应时,多瑞吉联合伽玛刀不失为临床难治性癌痛姑息镇痛治疗的一种较好选择。
Objective To observe the clinical efficacy and adverse reactions of Du Ruiji combined with gamma knife in the treatment of advanced intractable cancer pain. Methods Forty patients with advanced solid tumors who were refractory to cancer pain were treated with Doric and non-steroidal anti-inflammatory drugs. At the same time, spiral CT was used to scan and locate the tumor. According to the nature, type and site of the tumor, Body gamma knife treatment. Chief complaint of pain classification (VAS method) for pain assessment. Results The effective pain relief rate [complete remission (CR) + partial remission (PR)] was 96%. Conclusions Dorothy combined with Gamma Knife is a good choice for the treatment of palliative analgesia in refractory and refractory cancer when morphine painkiller can not tolerate or cause adverse reactions in advanced refractory cancerous pain.