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目的:考察药师对门诊抗菌药物注射剂联用实施干预后,药品不良反应发生率、不合理用药比例、日均费用的变化情况。方法:采用对照、前瞻性研究方法,选取干预前门诊输液中心记录中符合入选标准的500例患者为对照组;药师对门诊抗菌药物注射剂联用进行干预后,收集符合入选标准的500例患者为试验组。建立数据库,将结果进行统计、分析。结果:试验组与对照组比较,用药不合理例数对照组52例,试验组21例;不良反应和不良事件对照组18例,试验组9例;日平均费用试验组较对照组下降29.84元。结论:通过药师实施抗菌药物注射剂联用干预措施,可减少其不合理应用,降低不良反应发生率和药费。
OBJECTIVE: To investigate the change of adverse drug reaction rate, irrational drug use rate and average daily cost of pharmacists after the combination of antibacterial injections and outpatient interventions. Methods: A controlled, prospective study was conducted to select 500 outpatient infusion center records that meet the inclusion criteria for the control group. Pharmacists intervening with outpatient antimicrobial injections and collecting 500 eligible patients test group. Establish a database, the results of statistical analysis. Results: Compared with the control group, there were 52 cases in the control group and 21 cases in the experimental group, 18 cases in the control group and 9 cases in the control group, and 29.84 yuan in the daily average cost test group as compared with the control group . Conclusion: Through the implementation of antibacterial drug injections by pharmacists with interventions, it can reduce its unreasonable application, reduce the incidence of adverse reactions and drug costs.