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目的探讨思他宁联合美常安治疗重症急性胰腺炎(SAP)的疗效。方法将2005年至2009年SAP患者35例设为A组,按照SAP常规处理原则予监护、止痛、禁食、胃肠减压、抑酸、抗生素、纠正水电解质酸碱平衡治疗及给予静脉持续滴注思他宁(250μg/h),连用5~10 d;另将SAP患者45例设为B组,B组在A组治疗方案基础上加用美常安治疗。比较2组治疗效果。结果 2组腹痛腹胀症状缓解时间、住院时间及肠道菌群数量变化情况比较差异均有统计学意义(P<0.05)。结论思他宁联合美常安治疗SAP较单纯常规治疗更高效安全。
Objective To investigate the efficacy of Stilamin in combination with Mei Chang An in the treatment of severe acute pancreatitis (SAP). Methods A total of 35 patients with SAP from 2005 to 2009 were enrolled in group A. Patients were treated with routine SAP care, analgesia, fasting, gastrointestinal decompression, acid suppression and antibiotics, correcting the acid-base balance of water and electrolyte, Dripping Sitinine (250μg / h), once every 5 to 10 days; the other 45 cases of SAP patients were set to B group, B group in the A group based on the treatment program with the United States Changan treatment. Compare the treatment effect of 2 groups. Results There were significant differences between the two groups in the symptom relief, the length of hospital stay and the changes of intestinal microfacies (P <0.05). Conclusion Stilamin combined with the United States Changan treatment of SAP more simple and effective than the conventional treatment of safety.