接种牛痘苗后发生肾病综合征十分罕见,我们收治一例。患儿,男,2岁,因面部浮肿,尿急尿频等而急诊入院。患儿于1979年4月初接种牛痘苗(江西生物制品所生产,失效期1979年6月),第4天出现加重反应,整个发痘经过呈原发反应过程。4月23日出现面部及双下肢浮肿,并有尿频尿急,在当地治疗不见好转,于5月1日转入烟台市人民医院。 Nephrotic syndrome occurs after vaccination of vaccinia is very rare, we admitted to a case. Children, male, 2 years old, due to facial edema, urinary urgency, etc. emergency admission. Children in early April 1979 vaccinated vaccinia (Jiangxi biological products produced by the expiration of 1979 June), the first four days of aggravating reaction, the entire hair pox was primary reaction process. April 23 facial and lower extremity edema, and urinary urgency, the local treatment did not improve, on May 1 into the Yantai People’s Hospital.