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相对危险度的估计表示危险因素与疾病之间的联系程度,并未考虑到因素在人群中的流行率,因此不能估计人群由于暴露于危险因素后所发生疾病的比例,故在流行病学研究中,当确定了病因学的联系后,需进一步探讨人群归因危险度比。本文讨论了病例对照研究资料人群归因危险度比的估计方法,包括非配对资料、分级资料及配对资料的几种方法,并以胆固醇与高血压关系的资料作实例予以说明,最后探讨了人群归因危险度比在流行病学中的实用意义。
Relative risk estimates indicate the degree of association between risk factors and disease and do not account for the prevalence of factors in the population and therefore can not be estimated as a proportion of the population of diseases that occur after exposure to risk factors. , When the relationship between the etiology has been established, we need to further explore the attribution of the risk ratio of the population. This article discusses the method of estimating attribution hazard ratio for case-control study population, including non-paired data, graded data and paired data, and illustrates the relationship between cholesterol and hypertension as an example. Finally, Attribution of risk than in epidemiology of practical significance.