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目的 对哮喘豚鼠选择最佳的中药给药时间，以充分发挥药效，提高治疗效果。方法 选择市售桂龙咳喘宁胶囊，将哮喘豚鼠随机分 5个实验组，观察各组豚鼠哮喘发作的情况。结果 于 21时 1次给药组较其他时间给药的方法好 (P0.05)。结论 应用中医阴阳理论， 21时给药方法能充分利用豚鼠体内昼夜阴阳节律，更好地发挥中药升阳抑阴的作用，起到事半功倍的治疗效果。
Objective To select the best duration of traditional Chinese medicine for asthma guinea pigs so as to give full play to its efficacy and improve its therapeutic effect. Methods The selected Guilongkechuanning capsules were selected and asthmatic guinea pigs were randomly divided into 5 experimental groups to observe the asthma attack in each group of guinea pigs. Results The method of administration at 21:00 was better than other methods (P<0.05). Conclusion Applying the yin and yang theory of traditional Chinese medicine, the 21st-day administration method can make full use of the circadian rhythm of yin and yang in guinea pigs, and better play the role of the sun in suppressing yin and suppressing yin in guinea pigs, which can achieve a multiplier effect.