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作者利用18只豚鼠进行单侧内淋巴囊和管闭塞术产生内淋巴积水。术后1～18个月12耳进行透射电镜观察,3个月后6耳测定椭圆囊和半规管暗细胞区细胞内离子浓度。结果:3个月时暗细胞结构,细胞内钙和镁离子浓度未见明显改变,而细胞内K/Na比近乎减少一倍。术后18个月,透射电镜示暗细胞内空泡形成,基底皱褶减少,表面降解的耳石增多。在积水的
The authors used 18 guinea pigs to produce endolymphatic hydrops by unilateral lymphatic sac and tube occlusion. After 1 to 18 months 12 ears were observed by transmission electron microscopy, 3 months after 6 ears determination of intraocular cells and semi-regulatory cell dark cell ion concentration. Results: At 3 months, there was no significant change of dark cell structure, intracellular calcium and magnesium ion concentration, while the intracellular K / Na ratio nearly doubled. Eighteen months after operation, the transmission electron microscopy revealed the formation of vacuoles in the dark cells, reduced basal folds, and increased otoliths on the surface. In the water