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目的研究不同心肌Ganau构型的高血压患者血清NT-proBNP浓度的变化。方法选取2009年6月—2010年6月于心内科门诊及心内科病房就诊的高血压患者共184例,按照不同心肌构型分为四组,左室正常构型组(A组),左室向心性重构组(B组),左室向心性肥厚组(C组),以及左室离心性肥厚组(D组),并测定各组血清NT-proBNP的浓度进行统计学分析。结果各组间血清NT-proBNP的浓度存在明显差异,P值均<0.05。结论随着心肌构型严重性的改变,血清NT-proBNP浓度也逐渐明显升高。
Objective To study the changes of serum NT-proBNP concentrations in hypertensive patients with different cardiac Ganau conformations. Methods A total of 184 hypertensive patients admitted to Cardiology Department and Cardiology Department from June 2009 to June 2010 were selected and divided into four groups according to different myocardial configurations: normal left ventricular group (A group), left normal group Ventricular concentric remodeling group (group B), left ventricular concentric hypertrophy group (group C), and left ventricular eccentric hypertrophy group (group D). Serum concentrations of NT-proBNP in each group were determined for statistical analysis. Results Serum NT-proBNP concentrations were significantly different between groups, P <0.05. Conclusions With the change of myocardial structure severity, serum NT-proBNP concentration also gradually increased.