垂体GH腺瘤系激素分泌性垂体瘤中常见的一种。光镜检查多为嗜酸性细胞瘤,少数为嫌色细胞瘤,或两者的混合瘤。电镜检查及免疫组化染色为含有生长激素分泌颗粒的GH细胞。形态学上又将其分为浓密颗粒型和稀疏颗粒型两种。瘤细胞内分泌颗粒的多少主要反映激素贮存的程度,而不是内分泌功能的活跃程度。 Pituitary GH adenoma is a common type of hormone-secreting pituitary tumor. Most of the light microscopic examinations were eosinophils, a few were chromophobe, or mixed tumors of the two. Electron microscopy and immunohistochemical staining were GH cells containing growth hormone secreting granules. Morphologically, it is divided into two types: dense granules and sparse granules. The number of endocrine granules in a tumor cell mainly reflects the degree of hormone storage rather than the activity of endocrine function.