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目的检测冠心病中急性冠脉综合征(ACS)患者血清中高灵敏度C反应蛋白(hs-CRP)的水平,以探讨其在冠心病急性冠脉综合征中临床危险度分层的应用价值。方法用免疫比浊方法,分别测定60例ACS患者入院时hs-CRP水平,并测定30例稳定型心绞痛及30例健康成人hs-CRP作对照。结果 ACS组的hs-CRP水平为(12.05±2.48)mg/L,较正常对照组的(2.21±1.16)mg/L高(P<0.05);较稳定型心绞痛组(2.31±1.21)mg/L高(P<0.05),稳定型心绞痛组(2.31±1.21)mg/L较正常对照组(2.21±1.16)mg/L差异无统计学意义(P>0.05)。结论 hs-CRP与ACS发生有关,可作为危险分层的指标之一。
Objective To investigate the serum hs-CRP level in patients with acute coronary syndrome (ACS) in coronary heart disease (CHD) to explore the clinical value of hs-CRP in the clinical risk stratification of patients with acute coronary syndrome (CHD). Methods The levels of hs-CRP in admission of 60 patients with ACS were measured by immunoturbidimetry. Thirty patients with stable angina pectoris and 30 healthy adults were enrolled as control. Results The hs-CRP level in ACS group was (12.05 ± 2.48) mg / L, which was significantly higher than that in control group (2.21 ± 1.16) mg / L (2.31 ± 1.21 mg / L (2.31 ± 1.21) mg / L in stable angina pectoris group were significantly higher than those in normal control group (2.21 ± 1.16) mg / L (P <0.05). Conclusion hs-CRP is associated with the occurrence of ACS and may be used as one of the indicators of risk stratification.