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口服吗啡制剂已成为近年来治疗晚期癌痛的主要途经。由于疼痛治疗的目的是有效地预防疼痛的发生而不仅是出现疼痛症状后的治疗,因此口服给药的间隔必须是在上一次给药的药效消失之前。吗啡的血浆半衰期较短,为2.5～3小时。为获得最佳止痛效果和最小副作
Oral morphine preparations have become the main route for the treatment of advanced cancer pain in recent years. Since the purpose of pain therapy is to effectively prevent the occurrence of pain and not only the treatment after the appearance of pain symptoms, the oral administration interval must be before the efficacy of the previous administration disappears. Morphine has a short plasma half-life of 2.5 to 3 hours. For best analgesia and minimal side effects