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目的观察异甘草酸镁联合门冬氨酸鸟氨酸对重型肝炎的临床疗效。方法 75例重型肝炎患者,随机分为治疗组及对照组。对照组给予常规综合治疗;治疗组在综合治疗基础上,给予异甘草酸镁联合门冬氨酸鸟氨酸静滴,疗程为4周。治疗4周后比较两组患者的临床疗效及生化指标。结果治疗组的肝功能得到改善,凝血酶原活动度升高(P<0.01),治疗有效率增加(P<0.05)。结论在综合治疗基础上联用异甘草酸镁和门冬氨酸鸟氨酸能增强重型肝炎的疗效。
Objective To observe the clinical effect of magnesium isoglycyrrhizinate combined with aspartate ornithine on severe hepatitis. Methods 75 patients with severe hepatitis were randomly divided into treatment group and control group. The control group was given conventional comprehensive treatment. The treatment group was given intravenous injection of orgagarin combined with aspartate ornithine for 4 weeks on the basis of comprehensive treatment. After 4 weeks of treatment, the clinical efficacy and biochemical indexes of two groups were compared. Results The liver function of the treatment group was improved, the prothrombin activity increased (P <0.01), and the treatment efficiency increased (P <0.05). Conclusion Combination therapy with magnesium isoglycyrrhizinate and ornithine can enhance the therapeutic effect of severe hepatitis.