J酸是重要的染料中间体。有人用纸层析或薄板层析,对其主要杂质进行分离和定性,并给出半定量结果,耗时长,准确度也受到一定限制。近年来,离子对色谱技术发展很快。离子对色谱法是在液相色谱流动相中,加入适宜的“反离子”,使与被测样品中可离解的亲水性有机组分结合成离子对,从而成为亲脂性化合物,并借助于不同离子对在两相中的分配差异而得以分离。文献利用十六烷基三甲基溴化铵为“反 J acid is an important dye intermediate. Some people use paper chromatography or thin-layer chromatography, the main impurities of their separation and qualitative, and give semi-quantitative results, time-consuming, accuracy is also subject to certain restrictions. In recent years, ion-pair chromatography has developed rapidly. Ion-pair chromatography is the addition of a suitable “counter-ion” to the mobile phase of the liquid chromatograph to combine the dissociable hydrophilic organic component of the sample under test into an ion pair to become a lipophilic compound and, by means of Different ions are separated in the distribution of the two phases to be separated. The literature uses cetyl trimethyl ammonium bromide as "anti