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目的:观察骨复活汤对实验性激素性股骨头坏死血液流变学的影响。方法:将32只成年雄性新西兰家兔随机分为病理模型组、正常对照组、骨复活汤低剂量组及骨复活汤高剂量组,采用臀部注射醋酸氢化泼尼松,建立股骨头骨细胞坏死模型,观察血液流变学指标,进行分析比较。结果:骨复活汤可明显降低全血低切粘度、血浆粘度、红细胞压积含量。结论:骨复活汤对家兔激素性股骨头坏死有明显防治作用。
Objective: To observe the effect of Gufuhuo Tang on hemorheology of experimental steroid-induced femoral head necrosis. METHODS: Thirty-two male adult New Zealand rabbits were randomly divided into pathological model group, normal control group, Gufuhuotang low-dose group and Gufuhuotang high-dose group. Hip injection of prednisolone acetate was used to establish femoral head necrosis model. Observe the indicators of hemorheology and compare them. Results: Gu Fu Huo Tang can significantly reduce the whole blood hypoviscosity, plasma viscosity, hematocrit content. Conclusion: Gufuhuo Decoction has obvious preventive and therapeutic effects on rabbits with steroid-induced femoral head necrosis.