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以往曾报导在哮喘持续发作患者中发生癫痫持续状态,认为与支气管扩张药物运用有关。本文认为,哮喘急性发作期的成年患者所发生的抽搐明显地与氨茶硷有关。抽搐常为氨茶硷治疗的并发症,乃是儿童中熟知的一种毒性反应,但文献上只报告过几个成年病例。本文作者报导4例成年患者,年龄40～70岁,均有长期的支气管哮喘病史,无癫痫或其他发作性疾病既往史及家族史。在哮喘急性发作期住院治疗,用了多种药物,但均予氨茶硷0.25克每4小时一次至1克每6小时一次静滴,10～50小时后发生局限
It has been reported in the past in patients with persistent asthma episodes of status epilepticus, that the use of bronchodilators related. This article suggests that convulsions in adult patients during acute exacerbation of asthma are clearly related to aminophylline. Convulsions are often complications of aminophylline treatment, a well-known toxic reaction in children, but only a few adult cases have been reported in the literature. The authors report 4 adult patients, aged 40 to 70 years old, have a long history of bronchial asthma, no epilepsy or other seizures past disease history and family history. In the acute exacerbation of asthma hospitalization, with a variety of drugs, but both to aminophylline 0.25 g once every 4 hours to 1 g intravenously every 6 hours, 10 to 50 hours after the occurrence of limitations