Mller细胞是人视网膜内主要的神经胶质细胞之一,其突起分布于外界膜到内界膜,二级突起与神经元和胶质细胞密切接触,并可发挥重要的生理功能。糖尿病视网膜病变(diabetic retinopathy,DR)是糖尿病的主要并发症之一,其发病机制尚未完全清楚。近年来,随着对Mller细胞的深入研究,发现其在DR的发病和进展中起着重要的作用,本文就目前对Mller细胞的研究现状以及其在DR中的作用机制作一综述。 Mller cells are one of the major glial cells in the human retina. The protrusions distribute in the outer membrane to the inner limiting membrane, and the secondary protrusions in close contact with neurons and glial cells play an important physiological function. Diabetic retinopathy (DR) is one of the major complications of diabetes. Its pathogenesis is not yet fully understood. In recent years, with the in-depth study of Mller cells and found that it plays an important role in the pathogenesis and progression of DR, the current research on Mller cells and its mechanism of action in DR Summary.