论文部分内容阅读
目的 研究人疱疹病毒6型(HHV -6)感染与白血病的关系。 方法 用间接免疫荧光试验及聚合酶链反应,分别检测白血病22例和对照组15例血清中抗HHV- 6 IgG及外周血单个核细胞中HHV 6 DNA序列。 结果 白血病患者血清抗HHV -6 IgG的阳性率和滴度与对照组之间均无显著差异(P>0 .05);其HHV -6 DNA的检出率与对照组也无显著差异(P>0. 05)。 结论 HHV 6感染可能与白血病的发病无关。
Objective To study the relationship between human herpesvirus type 6 (HHV-6) infection and leukemia. Methods Indirect immunofluorescence assay and polymerase chain reaction were used to detect the sequence of HHV 6 DNA in anti-HHV-6 IgG and peripheral blood mononuclear cells in 22 cases of leukemia and 15 cases of control group respectively. Results The positive rate and titer of serum anti-HHV-6 IgG in leukemia patients were not significantly different from those in the control group (P> 0.05). The detection rate of HHV-6 DNA in leukemia patients was also not significantly different from that in the control group (P > 0. 05). Conclusion HHV 6 infection may not be related to the pathogenesis of leukemia.