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自身给药(self-administration)实验是用来评价药物精神依赖性潜力的一种实验方法,通过这种方法可观察到动物的主观觅药行为(d rug-seeking behavior),借以评价实验药物精神依赖性潜力的大小。建立自身给药动物模型首先进行一次手术,将一条医用硅橡胶管与动物的静脉系统相连接,通过金属背心、保护管与恒速输液泵形成一个密闭的输液系统。动物踏动物笼内的踏板,信号接收到计算机,由SACS实验程序按照科研人员的安排,根据动物的体重、实验进程、决定每次药物的注射量并响应动物的踏板要求自动控制恒速输液泵注射一次。
Self-administration experiments are an experimental method used to evaluate the psychic dependence of drugs, by which animals can be observed for their darby-seeking behavior in order to evaluate the spirit of the experimental drug The size of the potential for dependence. To establish its own animal model of administration First of all, an operation is to connect a medical silicone rubber tube to the animal’s venous system and form a closed infusion system through the metal vest, the protection tube and the constant speed infusion pump. According to the scientific research personnel’s arrangement, according to the weight of the animal and the experimental process, it determines the injection quantity of each drug and responds to the animal’s pedal requirements to automatically control the constant speed infusion pump Inject once.