防老剂 D 为橡胶工业中常用的防老剂,其主要成份为 N—苯基—2—荼胺(PBNA)。关于此品的致癌性,国外曾有所怀疑,甚至近年来的生产和使用量也大为减少,但目前尚不能确切证明。从1970年起,上海市工矿致癌因子协作组在调查中发现,有些橡胶工人癌症发病率偏高,因此在某橡胶厂作重点调查。在该厂癌症相对高发的第一车间的一些工段,测出空气中 PBNA 浓度偏高,而在另一癌症发生 Antioxidant D is commonly used in the rubber industry antioxidant, the main component of N-phenyl-2-tamine (PBNA). On the carcinogenicity of this product, foreign countries have been doubts, and even in recent years the production and use of greatly reduced, but it is not yet conclusive evidence. Since 1970, Shanghai Mining and Metallurgical Oncology Factor Collaboration Group found in the survey that some rubber workers have a high incidence of cancer, and therefore made a key investigation in a rubber factory. In some of the workshops in the first plant where the cancer was relatively high, the PBNA concentration in the air was measured to be high and in another cancer