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目的调查广东某地新生儿体内重金属水平并探讨其与低出生体重关系。方法采用方便抽样方法选择在广东省韶关2所医院分娩的1 036名孕妇进行问卷调查,同时采集新生儿脐带血,采用电感耦合等离子体质谱仪(ICP-MS)测量脐带血中的砷、镉等金属含量。结果在测量的金属中,金属砷的超标率最高,为72.49%,锑为48.07%,硒为34.07%,锰为27.12%,钡为14.48%;93.24%脐带血中钙偏低,46.81%铁偏低,94.11%铜偏低,64.19%锌偏低。除金属锰外,其他金属均与低出生体重相关;低出生体重组脐带血中砷、镉、锑、钡等几种重金属含量高于非低出生体重组,镁、钙、铁等必需金属含量低于非低出生体重组。结论调查地区部分重金属污染较严重,部分必需金属缺乏较严重,低出生体重与大部分金属相关。
Objective To investigate the levels of heavy metals in neonates in a certain area of Guangdong and to explore their relationship with low birth weight. Methods One hundred and thirty-three pregnant women who gave birth in two hospitals in Shaoguan of Guangdong Province were selected by the method of convenience sampling to collect the cord blood of newborns. The levels of arsenic and cadmium in cord blood were measured by ICP-MS Other metal content. Results Among the metals tested, the over-standard rates of arsenic were 72.49%, 48.07% for antimony, 34.07% for selenium, 27.12% for manganese and 14.48% for barium, while the low Ca in 93.24% cord blood was 46.81% Low, 94.11% copper is low, 64.19% zinc is low. The contents of arsenic, cadmium, antimony and barium in low birth weight group were higher than those in non-low birth weight group, and the contents of essential metals such as magnesium, calcium and iron Lower than non-low birth weight group. Conclusions Some of the heavy metal pollution in the surveyed area is more serious, and some of the necessary metal deficiency is more serious. The low birth weight is related to most metals.