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目的分析2011-2012年我院收治65例重症手足口病患儿的并发症、流行病学特征和病原学分类,为控制手足口病提供科学依据。方法 2011-2012年65例手足口重症病例的流行病学资料进行回顾性分析。结果重症手足口病例65例,集中出现在春夏季,男性多于女性,发病年龄以3岁以下儿童为主(95.38%)。所有患儿均有发热和皮疹(100%),出现中枢神经系统并发症(central nervous system complication,CNSC)者63例(96.92%)。在实验室确诊病例中,20例为EV71感染;11例为CoxA16;13例为其他肠道病毒。病原学检测以EV71感染为主。结论2011-2012年重症手足口病例主要为EV71感染,早期发现和救治重症病例是降低病死率的关键。
Objective To analyze the complication, epidemiological characteristics and etiological classification of 65 cases of severe hand-foot-mouth disease admitted to our hospital from 2011 to 2012 in order to provide a scientific basis for the control of hand-foot-mouth disease. Methods The epidemiological data of 65 cases of hand, foot and mouth severe cases from 2011 to 2012 were analyzed retrospectively. Results 65 cases of severe cases of hand, foot and mouth disease mainly concentrated in spring and summer, more men than women, the age of onset of children under 3 years of age (95.38%). All children had fever and rash (100%), 63 (96.92%) had central nervous system complication (CNSC). Of the laboratory-confirmed cases, 20 were EV71; 11 were CoxA16; and 13 were other enteroviruses. Etiological testing to EV71 infection. Conclusion The main cases of severe hand-foot-mouth disease in 2011-2012 are EV71 infection. Early detection and treatment of severe cases are the key to reducing mortality.