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目的:探讨血清甲胎蛋白水平对评估急性病毒性肝炎患者预后的价值。方法:采用微粒子酶免疫法检测106例急性病毒性肝炎患者入院时的血清甲胎蛋白水平,动态监测其肝功能、凝血项指标,分析甲胎蛋白水平与疾病预后之间的相关性。结果:106例急性病毒性肝炎患者的血清甲胎蛋白水平与急性病毒性肝炎的预后呈负相关性(r=-0.743,p<0.001)。结论:血清甲胎蛋白水平可以用来判断急性肝炎患者的预后。
Objective: To investigate the value of serum alpha-fetoprotein in evaluating the prognosis of patients with acute viral hepatitis. Methods: The levels of serum alpha-fetoprotein in 106 patients with acute viral hepatitis at admission were detected by microparticle enzyme immunoassay. The indexes of hepatic function and coagulation were dynamically monitored. The correlation between alpha-fetoprotein and prognosis was analyzed. Results: The serum alpha-fetoprotein level in 106 patients with acute viral hepatitis was negatively correlated with the prognosis of acute viral hepatitis (r = -0.743, p <0.001). Conclusion: Serum alpha-fetoprotein levels can be used to determine the prognosis of patients with acute hepatitis.