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本实验利用正常小鼠和荷瘤小鼠（Ｓ１８０肉瘤）为模型，对低剂量辐射抑制肿瘤发生、发展作用及对遗传物质的影响进行了研究。结果表明，小鼠预先经低剂量辐射处理后，对随后种植的民Ｓ１８０肉瘤细胞的植入率，比直接接种组明显降低（Ｐ＜０．０５），肿瘤生长缓慢。低剂量预先照射可增强淋巴细胞程序外ＤＮＡ合成能力，降低荷瘤所致骨髓细胞染色体畸变率。
In this study, normal mice and tumor-bearing mice (S180 sarcoma) were used as models to study the effects of low dose radiation on tumorigenesis, development and genetic material. The results showed that the implantation rate of the S180 sarcoma cells which were planted later was significantly lower (P <0.05) than that of the direct inoculation group after the mice were pre-treated with low dose of radiation. The tumor growth was slow. Low dose of pre-irradiation can enhance the ability of DNA synthesis outside the lymphocyte program to reduce chromosome aberration rate of bone marrow cells caused by tumor-bearing.