论文部分内容阅读
目的探讨磁共振扩散加权成像技术(DWI)在脑泡型包虫病与高级别脑胶质瘤鉴别诊断中的应用价值。方法选择2009—2015年及2013—2014年在新疆医科大学第一附属医院分别确诊为脑泡型包虫病患者11例(有效病灶23个)及高级别(WHOⅢ~Ⅳ级)的脑胶质瘤患者20例(有效病灶20个);应用3.0T磁共振仪,分别对患者进行全脑常规MR平扫、增强扫描及DWI检查。分别测量病灶实质区、水肿区(病灶周边0~10mm范围水肿区)及对照区(对侧相应部位的正常脑实质区)的表观扩散系数(ADC)值,并进行统计学分析。结果脑泡型包虫病与高级别脑胶质瘤实质区ADC值比较,差异有统计学意义(t=-5.593,P<0.01),胶质瘤实质区的ADC值大于脑泡型包虫病实质区;脑泡型包虫病与高级别脑胶质瘤水肿区ADC值比较差异有统计学意义(t=-2.825,P<0.01),胶质瘤水肿区的ADC值大于脑泡型包虫病水肿区。结论 DWI与常规MRI联合应用,可为脑泡型包虫病与高级别脑胶质瘤的诊断及鉴别诊断提供有价值的信息。
Objective To investigate the value of diffusion weighted imaging (DWI) in the differential diagnosis of cerebral echinococcosis and high-grade gliomas. Methods Eleven patients (23 effective lesions) and high grade (WHO grade Ⅲ ~ Ⅳ) brain glia were diagnosed in the First Affiliated Hospital of Xinjiang Medical University from 2009 to 2015 and from 2013 to 2014 respectively. Tumor patients in 20 cases (20 valid lesions); application of 3.0T magnetic resonance imaging were performed on patients with conventional brain MR plain scan, enhanced scanning and DWI examination. Apparent diffusion coefficient (ADC) values were measured in the parenchyma area, edema area (0 ~ 10mm edema area around the lesion area) and the control area (normal parenchyma area on the opposite side), respectively. Statistical analysis was performed. Results There was significant difference in the ADC value between the brain edema and the high grade gliomas (t = -5.593, P <0.01). The ADC value in the parenchyma of the glioma was higher than that in the brain There was significant difference in the ADC value between edema and edema in high grade gliomas (t = -2.825, P <0.01). The ADC value in glioma edema area was larger than that in the glomerulus Hydatid disease edema area. Conclusion The combination of DWI and conventional MRI may provide valuable information for the diagnosis and differential diagnosis of cerebral echinococcosis and high-grade gliomas.