Ｐ５３基因及人乳头瘤病毒（ＨＰＶ）与宫颈病变有着密切的关系［１，３］，因此，了解各种宫颈病变时Ｐ５３基因及 ＨＰＶ感染的情况，对于防治子宫颈癌具有重要价值。我们共选择１００例中、重度糜烂病例和４０例宫颈癌病例，进行了有关的研究。现将结果报告如下：１　材料和 P53 gene and human papillomavirus (HPV) are closely related to cervical lesions [1, 3]. Therefore, understanding the status of P53 gene and HPV infection in various cervical lesions is of great value in the prevention and treatment of cervical cancer. We have selected 100 cases of moderate and severe erosions and 40 cases of cervical cancer and conducted relevant studies. The results are now reported as follows: 1 Materials and