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脑是人体对缺氧最为敏感的器官,脑组织缺血将会导致局部脑组织及其功能的损害。临床上处理脑缺血性损伤的原则是尽早恢复血液再灌注,使缺血脑组织重新得到氧的供应。然而缺血后的血流恢复在某些情况下能导致进一步的组织损伤和功能障碍[1]。纳洛酮具有高脂溶性,能通过血-脑屏障
Brain is the body’s most sensitive to hypoxia organs, brain tissue ischemia will lead to local brain damage and function. The principle of clinical treatment of cerebral ischemic injury is to restore blood reperfusion as soon as possible, so that ischemic brain tissue to regain the supply of oxygen. However, post-ischemic blood flow recovery can lead to further tissue damage and dysfunction in some cases [1]. Naloxone has high fat solubility and can cross the blood-brain barrier