本院儿科自1994年1月～1999年12月共收治小儿瑞氏综合征4例,现分析如下。 1 临床资料 1.1 一般资料:4例中3例为婴幼儿,1例5岁;2例来自农村,2例来自城镇;发病前无捂热史,无家族性遗传病史。 1.2 临床表现:1例类似中毒性休克合并呼吸衰竭起病,4例均有发热、惊厥、恶心呕吐及意识障碍、颅内压增高,抽搐最少3次,最多达60次以上,昏迷持续2～14天,2例有消化道大出血及失血性休克。 Pediatric hospital from January 1994 to December 1999 were treated children with Reye’s syndrome in 4 cases, are analyzed as follows. 1 Clinical data 1.1 General information: 4 cases in 3 cases of infants and young children, 1 case of 5 years old; 2 cases from rural areas, 2 cases from cities and towns; before onset without cover heat history, no family history of genetic disease. 1.2 Clinical manifestations: a case of similar toxic shock with respiratory failure onset, 4 patients had fever, convulsions, nausea and vomiting and disturbance of consciousness, increased intracranial pressure, convulsions at least 3 times, up to 60 times more, coma lasting 2 ~ 14 days, 2 cases of gastrointestinal bleeding and hemorrhagic shock.