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目的了解克拉玛依市静脉注射吸毒与HCV感染的现况,探讨相关行为因素与HCV感染之间的关联强度。方法以克拉玛依市2009年-2011年看守所和拘留所在押人员作为研究对象,对该人群丙肝感染情况及其相关因素进行非条件Logistic回归分析。结果研究人群HCV感染阳性率为8.64%,其中有注射毒品行为者HCV感染阳性率为47.51%,注射毒品与HCV感染阳性之间的关联系数为0.3876(χ2=378.4668,P=0.0001)。有注射毒品行为者感染HCV的风险是无注射毒品行为者的11.77倍(95%CI为8.01~17.31);其次是民族因素,少数民族感染HCV的风险是汉族的2.38倍(95%CI为1.62~3.48),性乱行为与HCV感染的关联系数为0.0501。结论静脉注射吸毒、少数民族是丙型肝炎病毒感染的高危因素,因此,以当地多种文字和语言加大宣传力度,提倡培养健康生活行为方式,在静脉注射吸毒人群中宣传一人一针和不共用针具等,对于降低本地HCV感染率将起到至关重要的作用。
Objective To understand the current status of intravenous drug use and HCV infection in Karamay City and to explore the correlation between relevant behavioral factors and HCV infection. Methods The detainees in detention center and detention center from 2009 to 2011 in Karamay were investigated. Logistic regression analysis was conducted on the prevalence of hepatitis C and its related factors in this population. Results The positive rate of HCV infection in the study population was 8.64%. The positive rate of HCV infection among injecting drug users was 47.51%. The correlation coefficient between injecting drug and HCV infection was 0.3876 (χ2 = 378.4668, P = 0.0001). The risk of contracting HCV was 11.77 times (95% CI: 8.01-17.31) for injecting drug users, followed by ethnics. The risk of HCV infection among ethnic minorities was 2.38 times that of Han nationality (95% CI: 1.62 ~ 3.48). The correlation coefficient between sexual disorder and HCV infection was 0.0501. Conclusions Intravenous drug abuse and ethnic minorities are risk factors for hepatitis C virus infection. Therefore, we should step up publicity efforts in a variety of local languages and languages to promote healthy lifestyles and promote one-person and one-person vaccination among intravenous drug users Sharing needle, etc., will play a crucial role in reducing the local HCV infection rate.