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对100例哮喘患儿进行淋巴细胞亚群及体液免疫功能检测。结果表明:哮喘发作组与正常对照组比较CD_3~+及CD_8~+明显下降;CD_4~+、CD_(20)~+及CD_4~+/CD_8~+比值明显上升,IgE明显上升,IgG明显下降。缓解组细胞及体液免疫各指标均随病情好转趋向正常范围。脱敏治疗前与对照组比较各指标变化与哮喘发作组相近。脱敏治疗后CD_3~+、CD_4~+、CD_8~+及CD_4~+/CD_8~+比值均与对照组无统计学差异。
100 cases of children with asthma lymphocyte subsets and humoral immune function test. The results showed that the ratio of CD_4 ~ +, CD_ (20) ~ + and CD_4 ~ + / CD_8 ~ + in asthma attack group was significantly lower than that in normal control group, IgE increased significantly, IgG decreased significantly . Relieving group of cells and humoral immunity indicators are improved as the disease tends to the normal range. Before desensitization treatment compared with the control group changes in various indicators and asthma attack group similar. After desensitization treatment, the ratios of CD_3 ~ +, CD_4 ~ +, CD_8 ~ + and CD_4 ~ + / CD_8 ~ + were not significantly different from the control group.