Inhibitory Effect of HCPT on Expression of HIF-1α and Downstream Genes in Hypoxic Human Cervical SiH

来源 :Journal of Huazhong University of Science and Technology(Med | 被引量 : 0次 | 上传用户：toforworld

【摘要】

：

The hypoxic model to simulate hypoxic microenvironment in solid tumors was established and the effect of hydrocamptothecin(HCPT) on the hypoxia-induced over-exp

【作者】

：

施薇于世英

【机构】

：

CancerCenter

【出处】

：

Journal of Huazhong University of Science and Technology(Med

【发表日期】

：

2007年5期

【关键词】

：

宫颈癌喜树碱 HIF-1Α 下游基因缺氧 hydrocamptothecin HIF-1α VEGF cervical cancer

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The hypoxic model to simulate hypoxic microenvironment in solid tumors was established and the effect of hydrocamptothecin(HCPT) on the hypoxia-induced over-expression of HIF-1α and VEGF genes was explored.Human cervical cancer SiHa cells were cultured in

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Inhibitory Effect of HCPT on Expression of HIF-1α and Downstream Genes in Hypoxic Human Cervical SiH

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