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目的探讨6种肿瘤标志物(肿瘤特异性生长因子TSGF、癌胚抗原CEA、糖类抗原CA125、CA19-9、CA72-4、CA15-3)联合检测对于肺癌的诊断价值。方法 2011年9月至2012年9月期间,我院诊治的50例肺癌患者作为观察组,另选50例健康体检者作为对照组研究对象,分别进行6种肿瘤标志物的测定,以及其敏感度和特异度的比较。结果与对照组相比,观察组TSGF、CEA、CA125、CA72-4、CA15-3均明显升高,P<0.05,差异有统计学意义。结论 6种肿瘤标志物联合检测能够显著提高肺癌的临床诊断率,值得临床推广。
Objective To investigate the diagnostic value of combined detection of six kinds of tumor markers (tumor specific growth factor TSGF, carcinoembryonic antigen CEA, carbohydrate antigen CA125, CA19-9, CA72-4, CA15-3) for lung cancer. Methods From September 2011 to September 2012, 50 patients with lung cancer diagnosed and treated in our hospital were selected as the observation group and 50 healthy individuals were selected as the control group. The determination of 6 tumor markers and their sensitivity Degree and specificity of the comparison. Results Compared with the control group, the observation group of TSGF, CEA, CA125, CA72-4, CA15-3 were significantly increased, P <0.05, the difference was statistically significant. Conclusion The combined detection of six tumor markers can significantly improve the clinical diagnosis of lung cancer, it is worth clinical promotion.