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介绍了一种基质辅助激光解吸电离的进样方法-气溶胶进样方法．包含基质和分析物的气溶胶粒子在大气压力下直接进入气溶胶飞行时间质谱仪,粒子产生的散射光信号由光电倍增管收集,通过外部的时序电路,给出气溶胶粒子粒径的信息并触发266 nm Nd:YAG激光器,可以同时获得气溶胶粒子的粒径和基质辅助激光解吸电离质谱与其他的液体进样方式相比,它可以实现单粒子进样,因而样品消耗较少．主要研究了基质与分析物的摩尔比和激光能量对分析物离子信号的影响,合适的摩尔比和激光能量分别为50-110:1和200-400μJ．
A sample introduction method of matrix-assisted laser desorption ionization is introduced. The aerosol particles containing the matrix and the analyte go directly to the aerosol time-of-flight mass spectrometer at atmospheric pressure and the scattered light signals generated by the particles are collected by a photomultiplier tube. Via an external timing circuit, information on the aerosol particle size is given and triggered 266 nm Nd: YAG laser for simultaneous particle size and matrix-assisted laser desorption / ionization mass spectrometry It enables single-particle injections compared to other liquid injections, resulting in less sample consumption. The effects of matrix and analyte molar ratio and laser energy on the analyte ion signal were studied. The suitable molar ratio and laser energy were 50-110: 1 and 200-400μJ, respectively.