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用卵巢癌细胞短期培养,以MTT(噻唑蓝)吸收光度法进行抗癌药物敏感试验,预测16例卵奥癌在治疗前对顺铂等7种炕癌药物的体外敏感性,并与治疗后临床疗效比较。结果表明,使用敏感药物者的临床缓解率为92.7%,未测出敏感药物者(1例)临床未控制,敏感试验测定与疗效的一致性为87.5%。本方法简便、经济、快速、准确率较高,有助于化疗个体化,提高疗效。
Using short-term culture of ovarian cancer cells and anti-cancer drug sensitivity test by MTT (thiazolyl blue) absorption spectrophotometry, the sensitivity of 16 kinds of OAC cancer to 7 kinds of kang cancer drugs such as cisplatin before treatment was predicted, Clinical efficacy comparison. The results showed that the use of sensitive drugs clinical remission rate was 92.7%, did not detect any sensitive drug (1) clinical uncontrolled, sensitive test determination and efficacy of the consistency was 87.5%. The method is simple, economical, rapid and accurate, which helps to individualize chemotherapy and improve curative effect.