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目的比较宁夏回族和汉族女性乳腺癌发生的危险因素的不同,为预防和控制乳腺癌的发生提供依据。方法将2013年5月至2014年7月于宁夏医科大学附属总医院就诊入院的新发宁夏女性乳腺癌患者作为病例,选取来源于同一医院同期入院的无乳腺癌的女性患者作为对照,对二者使用统一的调查表进行流行病学调查,调查内容包括一般人口学资料、月经史、生育史、生活习惯和肿瘤家族史等其他乳腺癌易感因素。采用多因素logistic回归分析比较回族和汉族乳腺癌发生的危险因素。结果多因素logistic回归分析显示,流产总数(OR=2.631,P=0.028)是回族女性乳腺癌发生的危险因素,体育锻炼(OR=0.177,P=0.040)是其保护因素。直系亲属患肿瘤(OR=4.249,P=0.014)、流产总数(OR=1.602,P=0.001)、首次生育年龄(OR=1.253,P=0.001)和初婚年龄(OR=1.223,P=0.001)是汉族女性乳腺癌发生的主要危险因素,体育锻炼(OR=0.422,P=0.001)是其保护因素。结论回族和汉族女性乳腺癌发生的危险因素在流产总数、体育锻炼上比较一致,与回族相比,汉族女性初婚年龄、首次生育年龄和直系亲属患肿瘤在乳腺癌的发生中也发挥了一定的作用。
Objective To compare the different risk factors of breast cancer among Hui and Han women in Ningxia and to provide basis for preventing and controlling the occurrence of breast cancer. Methods From March 2013 to July 2014, Ningxia Female University Hospital of Ningxia Medical University Affiliated General Hospital of the newly diagnosed female patients with breast cancer as the case, selected from the same hospital admission women without breast cancer as a control, Using a uniform questionnaire for epidemiological survey, the survey contents include general demographic data, menstrual history, fertility history, lifestyle and family history of cancer and other breast cancer susceptibility factors. Multivariate logistic regression analysis was used to compare the risk factors of breast cancer among Hui and Han nationality. Results Multivariate logistic regression analysis showed that the total number of abortion (OR = 2.631, P = 0.028) was a risk factor for breast cancer in Hui women. Physical exercise (OR = 0.177, P = 0.040) was the protective factor. (OR = 1.223, P = 0.001), the first birth age (OR = 1.253, P = 0.001) and first marriage age Is a major risk factor for breast cancer in Han women. Physical exercise (OR = 0.422, P = 0.001) is the protective factor. Conclusions The risk factors of breast cancer in Hui and Han women are consistent with the total number of abortion and physical exercise. Compared with Hui people, the first marriage age, the first childbearing age and the incidence of breast cancer in Han women also play a certain role in breast cancer effect.