对南海小月柳珊瑚Menellasp.的化学成分进行研究。应用反复硅胶柱层析、Sephadex LH-20柱色谱和制备薄层等多种色谱方法进行分离和纯化。从中分离得到3个subergorane倍半萜和1个suberosane倍半萜化合物,利用波谱分析技术和文献比对等方法确定化合物的结构,分别为柳珊瑚酸(1),柳珊瑚酸甲酯(2),2β-羟基柳珊瑚酸甲酯(3)和suberosenol A(4)。以上化合物均为首次从小月柳珊瑚属(Menella)中分离得到。 The chemical composition of Menellasp. The compounds were isolated and purified by repeated silica gel column chromatography, Sephadex LH-20 column chromatography and preparative TLC. Three subergorane sesquiterpenes and one suberosane sesquiterpenoid compound were isolated from them. The structures of the compounds were determined by spectroscopic analysis and literature comparison. The structures of the compounds were as follows: , 2β-hydroxy-methylholac (3) and suberosenol A (4). The above compounds were isolated from Menella for the first time.