肝豆状核变性(Wilson 氏病)是一种具有家族倾向的疾病。多发生于7—8岁以后,临床表现有神经系统的锥体外束征、肝脏损害、精神症状、生化障碍(如血清铜蓝蛋白 Ceruloplasmin 减少)及尿铜排泄增加等改变。国外文献对本病迭有报导;国内文献解放前后亦报导60余例,可见本病在国内亦非罕见。然而,国内外文献均着重叙述神经系统的改变,对精神症状则很少提及,或略而不详,本文仅将5年来所遇到3例患 Wilson’s disease (Wilson’s disease) is a familial disorder. Occur in the 7-8 years old later, the clinical manifestations of neurological extrapyramidal signs, liver damage, mental symptoms, biochemical disorders (such as serum ceruloplasmin Ceruloplasmin reduction) and increased urinary copper excretion and other changes. Foreign literature has reported this disease; before and after the liberation of domestic literature also reported more than 60 cases, shows that the disease is not uncommon in the country. However, both domestic and foreign literatures focus on describing the changes of the nervous system, rarely mentioning the symptoms of the mind, or a little but not enough details. In this paper, only three cases