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本文选用“微量周血微核测试方法”对５０名石油沥青作业上人进行了该变形及微核率观察，结果观察组的两项指标明显高于对照组，Ｐ＜０．０１，均呈高度显著性差异。观察对象不同工龄组间两项指标检测结果比较，核变形、无显著性差异，Ｐ＞０．０５。而微核率１－５年则与６－１０年组比较，Ｐ＞０．０５，无显著性差异；６－１０年组与１１－年组比较Ｐ＜０．０５，有显著性差异；１－５年组与１１－年组比较，Ｐ＜０．０１，有高度显著性差异。吸烟又接触沥青使工人周血微核率明显高于单纯吸烟健康者，Ｐ＜０．０５，二者有显著性差异。
In this paper, “micro-week blood micronucleus test method” on 50 oil asphalt operations on the human were the deformation and micronucleus rate observed results of the two indicators were significantly higher than the control group, P <0.01, were Highly significant difference. Observed objects of different age groups between the two indicators test results compared nuclear deformation, no significant difference, P> 0.05. The micronucleus rate 1-5 years compared with 6-10 years group, P> 0.05, no significant difference; 6-10 years group and 11-year group P <0.05, significant difference; There was a highly significant difference between P <0.01 in the 1-5 year group and the 11-year group. Smoking and contact with asphalt so that workers micronucleus rate was significantly higher than pure smokers, P <0.05, a significant difference between the two.