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本实验证明,豚鼠爆震性听损伤经药物治疗后,可明显促使耳廓反射的恢复;早期治疗对耳蜗病变的恢复有显著效果,而晚期治疗的效果不佳。震后耳蜗病理改变的程度:未治组9耳,轻度病变者2耳,中度者4耳,重度者3耳;早治组14耳,轻度病变者8耳,中度者3耳,重度者3耳,两组对比有显着差异(P<0.05);而晚治组7耳,轻度病变者1耳,中度者3耳,重度者3耳,与未治组对照无显著差异(P>0.05)。震后观察了14～90天,所有29只豚鼠的耳蜗病变均未恢复正常。以上结果与临床疗效相符,用药物治疗爆震性听力损害虽有一定的效果,但完全治癒者较少.
This experiment shows that guinea pig detonation hearing impairment after drug treatment, can significantly promote the recovery of auricle reflex; early treatment of cochlear lesions have a significant effect of recovery, and the effect of late treatment is not good. The degree of pathological changes in the cochlea after shock was 9 cases in the untreated group, 2 ears in the mild disease group, 4 ears in the moderate condition and 3 ears in the severe condition; 14 ears in the early treatment group, 8 ears in the mild disease group and 3 ears in the moderate condition , Severe 3 ears, the two groups were significantly different (P <0.05); while the late treatment group 7 ears, mild lesions 1 ear, moderate 3 ears, severe 3 ears, compared with the control group Significant difference (P> 0.05). After the shock was observed for 14 to 90 days, all 29 guinea pigs had no cochlear lesions returned to normal. The above results and clinical efficacy consistent with the treatment of detonating hearing loss although a certain effect, but less complete cure.