红霉素是一种相对安全,使用广泛的抗菌素,据报道无肾脏毒性作用。作者报告1例红霉素引起的急性间质性肾炎。患者女性,39岁,因贫血及全身乏力入院。于6岁时曾患风湿热,已完全恢复。平时偶有上呼吸道感染,对症用药包括磷酸可待因、氨基比林及非那西汀。本次入院前,因反复发生扁桃体炎用红霉素数周。入院时体检发现明显贫血,可闻主动脉瓣喷射音及心尖部舒张期杂音,无浮肿及皮疹。关节不痛。无 Erythromycin is a relatively safe, widely used antibiotic, reportedly having no renal toxic effects. The authors report 1 case of erythromycin-induced acute interstitial nephritis. Female patient, 39 years old, admitted to hospital due to anemia and malaise. She had rheumatic fever at age 6 and has recovered completely. Occasionally occasional upper respiratory tract infection, symptomatic medication, including codeine phosphate, aminopyrine and phenacetin. Before admission, due to recurring tonsillitis with erythromycin for several weeks. Physical examination found significant anemia on admission, can be heard aortic valve sound and apical diastolic murmur, no edema and rash. Joints do not hurt. no