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目的观察酚妥拉明、间羟胺辅助治疗小儿重症肺炎的临床疗效。方法 134例患重症肺炎的小儿随机分为2组各67例,对照组给予积极抗感染、改善通气功能、加强营养、纠正酸中毒、电解质平衡、吸氧、利尿、强心,预防并发症,支持、对症治疗;治疗组在对照组治疗的基础上再给予酚妥拉明、间羟胺血管活性药物治疗。观察2组临床疗效的差异。结果对照组患儿总有效率77.61%,治疗组患儿总有效率88.06%,2组患儿总有效率比较差异有显著性。结论在综合治疗的基础上加用酚妥拉明、间羟胺能明显提高小儿重症肺炎的治疗效果。
Objective To observe the clinical efficacy of phentolamine and meta-hydroxylamine in the treatment of pediatric severe pneumonia. Methods Totally 134 children with severe pneumonia were randomly divided into two groups (n = 67 each). The control group was given active anti-infective to improve the ventilation function, strengthen nutrition, correct acidosis, electrolyte balance, oxygen, diuretic, cardiac, prevent complications, Support, symptomatic treatment; treatment group in the control group based on the treatment given phentolamine, meta-hydroxylamine vasoactive drug treatment. The difference of clinical efficacy between the two groups was observed. Results The total effective rate of children in the control group was 77.61%, the total effective rate in the treatment group was 88.06%. There was significant difference in the total effective rate between the two groups. Conclusions Based on the comprehensive treatment with phentolamine, meta-hydroxylamine can significantly improve the therapeutic effect of pediatric severe pneumonia.