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目的探讨幽门螺杆菌感染与缺铁性贫血发病的相关性及其临床意义。方法对40例缺铁性贫血伴有慢性胃炎患者,检测其血清铁、总铁结合力、铁蛋白及血红蛋白浓度,并对胃幽门螺杆菌进行检测。将幽门螺杆菌阳性者分为两组(A1、A2组)。A1组给予补铁及幽门螺杆菌根除治疗,A2组仅幽门螺杆菌根除治疗;治疗后复查上述指标。另以无贫血的慢性胃炎患者40例(B组)进行对照研究。结果缺铁性贫血伴慢性胃炎患者幽门螺杆菌感染率较高,联合补铁及抗幽门螺杆菌治疗疗效显著。结论幽门螺杆菌感染或幽门螺杆菌感染导致的慢性胃炎可成为缺铁性贫血的病因,补铁联合根除幽门螺杆菌的治疗为治疗缺铁性贫血提供了新的有效途径。
Objective To investigate the correlation between Helicobacter pylori infection and the incidence of iron deficiency anemia and its clinical significance. Methods Forty patients with iron deficiency anemia and chronic gastritis were tested for serum iron, total iron binding capacity, ferritin and hemoglobin concentration, and Helicobacter pylori in stomach was detected. Helicobacter pylori positive were divided into two groups (A1, A2 group). A1 group were given iron and Helicobacter pylori eradication therapy, A2 group only H. pylori eradication therapy; after treatment, review the above indicators. Another non-anemia patients with chronic gastritis in 40 cases (group B) control study. The results of iron deficiency anemia with chronic gastritis in patients with high rates of Helicobacter pylori infection, combined with iron and anti-helicobacter pylori treatment was significant. Conclusions Helicobacter pylori infection or chronic gastritis caused by Helicobacter pylori infection can be the cause of iron deficiency anemia. The combination of iron supplementation and helicobacter pylori eradication provides a new effective way to treat iron deficiency anemia.