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用荧光法研究木犀草素对大鼠腹腔巨噬细胞释放H_2O_2的影响。结果表明,木犀草素在不同浓度(4×10(-7)～10~(-5)mol/L)时,对酵母多糖诱导的大鼠腹腔巨噬细胞H_2O_2释放呈浓度依赖性的抑制,且以木犀草素与巨噬细胞共同培养4h抑制作用最明显。其作用机制有待进一步研究。
Effect of luteolin on the release of H_2O_2 from rat peritoneal macrophages using fluorescence spectroscopy. The results showed that luteolin had a concentration-dependent inhibition of H_2O_2 release from peritoneal macrophages induced by zymosan at different concentrations (4×10 (-7) to 10 (-5) mol/L). In addition, the inhibitory effect of luteolin and macrophage co-cultured for 4 h was most obvious. The mechanism of action needs further study.