视网膜母细胞瘤是儿童时期最常见的眼内恶性肿瘤。据上海地区调查,活产儿童发病数为1/11800。本病诊断虽不困难,但临床怀疑视网膜母细胞瘤而摘除眼球者,有10—30%未得到病理组织学证实。近年来应用房水、血清及超声检查有助于诊断,仍有部分疑难病例不能肯定,视网膜母 Retinoblastoma is the most common intraocular malignancy in childhood. According to a survey in Shanghai, the number of live births is 1/11800. Although the diagnosis of this disease is not difficult, but the clinical suspicion of retinoblastoma and removal of the eye, 10-30% have not been confirmed by histopathology. In recent years, the application of aqueous humor, serum and ultrasound help to diagnose, there are still some difficult cases can not be sure, retinal mother