论文部分内容阅读
[目的]观察溃结方保留灌肠联合美沙拉嗪治疗溃疡性结肠炎疗效。[方法]使用随机平行对照方法,将60例门诊患者按就诊顺序号简单随机分为两组。对照组30例美沙拉嗪,1g/次,3次/d,口服。治疗组30例溃结方(败酱草30g,白矾4g,五倍子6g,煅龙骨、煅牡蛎各30g,煅瓦楞子15g,白芨粉9g),1剂/d,浓煎至100m L,灌肠;美沙拉嗪治疗同对照组。连续治疗7d为1疗程。观测临床症状、血小板、红细胞沉积率(ESR)、C反应蛋白、结肠黏膜、不良反应。治疗1疗程(7d),判定疗效。[结果]治疗组显效23例,有效5例,无效2例,总有效率93.33%;对照组显效15例,有效8例,无效7例,总有效率76.67%;临床疗效两组无显著差异(P>0.05)。血小板计数、ESR、CRP两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01,P<0.05)。[结论]溃结方保留灌肠联合美沙拉嗪治疗溃疡性结肠炎,疗效满意,无严重不良反应。
[Objective] To observe the curative effect of ulcerative colitis treated with ursolum enema and mesalazine. [Methods] Using randomized parallel control method, 60 cases of outpatients were randomly divided into two groups according to the sequence number. Control group, 30 cases Mesalazine, 1g / time, 3 times / d, orally. The treatment group 30 patients with ulcerative side (Patrinia 30g, alum 4g, gallnut 6g, calcined keel, calcined oyster each 30g, calcined corrugated son 15g, white powder 9g), 1 / d, Mesalazine treatment with the control group. Continuous treatment 7d for a course of treatment. Clinical symptoms, platelets, erythrocyte sedimentation rate (ESR), C-reactive protein, colonic mucosa, adverse reactions were observed. Treatment of a course of treatment (7d), to determine the efficacy. [Results] In the treatment group, 23 cases were markedly effective, 5 cases were effective, 2 cases were ineffective, and the total effective rate was 93.33%. In the control group, 15 cases were markedly effective, 8 cases were effective, 7 cases were ineffective and the total effective rate was 76.67%. There was no significant difference between the two groups (P> 0.05). The platelet count, ESR and CRP both improved (P <0.01), and the treatment group improved better than the control group (P <0.01, P <0.05). [Conclusion] UCJE combined with mesalazine in the treatment of ulcerative colitis has satisfactory curative effect and no serious adverse reactions.