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目的 探讨影响梅毒孕产妇早产或分娩低出生体重儿的危险因素.方法 选择2016年浙江省确诊梅毒孕产妇为研究对象.采用非条件Logistic回归法分析梅毒孕产妇早产或分娩低出生体重儿的相关危险因素.结果 梅毒孕产妇早产或低出生体重发生率9.5％(233/2 449).多因素分析显示,婚姻状态为离异及其他(调整OR=1.609,95％CI:1.041 ～2.486)、既往产次1次或≥2次(调整OR=1.401和1.906,95％CI:1.021～1.921和1.251～2.903)、初检孕周≥28周(调整OR=1.535,95％CI:1.023～2.303)、TRUST/RPR滴度超过1:8(调整OR=1.569,95％CI:1.055～2.333)和确诊后未治疗(调整OR=1.993,95％CI:1.314～3.023)增加了梅毒孕产妇早产或分娩低出生体重儿的风险.结论 婚姻不稳定、多产次、初次产检晚、高血清学滴度和未治疗是梅毒孕产妇发生早产或低出生体重危险因素.“,”Objective To explore the incidence and risk factors of preterm birth or low birth weight among pregnant women with syphilis.Methods The pregnant women with syphilis were observed in 2016 in Zhejiang province and followed up by their pregnancy outcomes.Risk factors associated with preterm birth or low birth weight were estimated using the crude and adjusted odds ratios with multivariate logistic regression models.Results The incidence of preterm birth or low birth weight in syphilis positive pregnant women was 9.5％ (233/2 449).Multivariate logistic regression revealed that un-marital status (adjusted OR =1.609,95％ CI:1.041-2.486),1 previous parity (adjusted OR=1.401,95％CI:1.021-1.921),over 2 previous parities (adjusted OR=1.906,95％ CI:1.251-2.903),first antenatal care over 28 gestational weeks (adjusted OR =1.535,95％ CI:1.023-2.303),TRUST or RPR serum titer over 1:8 (adjusted OR=1.569,95％CI:1.055-2.333),and untreated (adjusted OR=1.993,95％CI:1.314-3.023) increased risk of preterm birth or low birth weight.Conclusions Unmarried,high number of parity,late in antenatal care,untreatment,higher TRUST or RPR serum titer are the risk factors of preterm birth and low birth weight among pregnant women with syphilis.