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于1984年6～8月和1985年6～11月进行了空肠弯曲菌肠道感染的临床及实验室研究。急性腹泻患儿216例,同期普查健康儿童856例作为对照。采取新鲜粪便,腹泻患儿培养出空肠弯曲菌25例(占11.6％),健康儿童对照组分离出该菌25例(占2.9％)(P<0.01),多数患儿年龄在3岁以下,性别分布无明显差异。25例培养阳性空肠弯曲菌患者的临床表现有少量血性和/或粘液粪便,发热和腹痛。本文对空肠弯曲菌做药敏试验观察,发现该菌对红霉素,庆大霉素,氯霉素和一些中草药如大黄,乌梅及大青叶等均敏感。上述药物可作为临床治疗的首选药物。此外新鲜粪便直接涂片,用1％硷性品红染色法,有很高的特异性和敏感性,在诊断空肠弯曲菌肠炎中是一种简便,迅速而可靠的方法。
Clinical and laboratory studies of C. jejuni enteric infections were performed in June-August 1984 and June-November 1985. 216 cases of children with acute diarrhea, 856 cases of healthy children in the same period as a control. 25 cases (accounting for 11.6%) of Campylobacter jejuni were cultured in fresh stool and diarrhea, 25 cases (2.9%) were isolated from healthy control group (P <0.01), most of them were under 3 years old, Gender distribution no significant difference. 25 patients with positive Campylobacter jejuni clinical manifestations of a small amount of bloody and / or mucus stool, fever and abdominal pain. In this paper, Campylobacter jejuni susceptibility test observations and found that the bacteria on erythromycin, gentamicin, chloramphenicol and some Chinese herbal medicines such as rhubarb, plum and leaves are sensitive. The above drugs can be used as the drug of choice for clinical treatment. In addition, direct application of fresh faeces with 1% alkaline fuchsine staining method, with high specificity and sensitivity in the diagnosis of Campylobacter jejuni enteritis is a simple, rapid and reliable method.